Brand
iS Clinical
Nationwide delivery across South Africa
Innovative Skincare, better known as iS Clinical, was founded in California in 2000 on a simple premise: botanical actives formulated to pharmaceutical standards. Its formulas are validated in independent clinical studies and used daily in professional skin clinics worldwide.
Shop the iS Clinical range in South Africa with nationwide delivery from SK1N. The line spans cleansers, clinically studied serums, moisturisers and sunscreens, all built around botanical actives formulated to pharmaceutical standards.
47 products
View all products
Treatment / iS Clinical
Active Peel System
R2254.00
Active Peel System from iS Clinical is a professional-grade, two-step resurfacing treatment across 15 treatment sets. It combines botanical acids, copper tripeptide-1, and vitamin A to improve clarity and reduce signs of pigmentation. This system provides a gentle yet effective exfoliation, leaving your skin feeling hydrated and protected for a more radiant appearance.
Earn 1127 SK1N Points
Eye Care / iS Clinical
GeneXC Firming Eye Gel
R2425.00
The 15ml GeneXC Firming Eye Gel by iS Clinical is an advanced treatment using vitamin C, peptides, and fruit acids to address ageing around the eyes. It helps to firm and brighten tired skin, delivering a smooth finish. Its lightweight texture absorbs into the orbital area to leave the delicate skin feeling refreshed and visibly more radiant.
Earn 1213 SK1N Points
Cream / iS Clinical
Daily Dynamic Hydrator 50g
R3174.00
Daily Dynamic Hydrator 50g acts as a lightweight, multi-tasking cream that reinforces your skin against environmental stressors with Ceramides and botanical antioxidants. It provides intense hydration to leave your complexion looking healthy and renewed. Simply massage a small amount of this cream over your face and neck every morning and evening to keep your skin feeling soft and protected.
Earn 1587 SK1N Points
Cleanser / iS Clinical
Cream Cleanser 120ml
R1176.00
The 120ml Cream Cleanser offers a gentle, moisturizing experience for dry or sensitive skin. Formulated with safflower seed oil and glycerin, it effectively dissolves impurities and makeup while soothing the barrier. Apply to damp skin and rinse away to reveal a clean, supple, and well-hydrated face.
Earn 588 SK1N Points
SPF / iS Clinical
Eclipse SPF 50+ 100g
R1225.00
Eclipse SPF 50+ provides broad-spectrum defense against UVA and UVB rays using a lightweight, water-resistant formula. This 100g tube contains Vitamin E, Zinc Oxide, and Titanium Dioxide to keep your complexion protected without a greasy feel. Apply this formula to your face and neck for a smooth, matte finish that lasts throughout your daily outdoor activities.
Earn 613 SK1N Points
SPF / iS Clinical
Eclipse SPF 50+ PerfecTint Beige 100g
R1225.00
Eclipse SPF 50+ PerfecTint Beige 100g offers superior water-resistant sun protection with a touch of color for a flawless, matte finish. This lightweight, non-greasy formula features Titanium Dioxide and Zinc Oxide to guard your skin against UVA and UVB damage. Use it daily by applying a liberal amount to your face and neck before heading out to enjoy your day.
Earn 613 SK1N Points
SPF / iS Clinical
Extreme Protect SPF 40 100g
R2082.00
Providing advanced environmental defense, Extreme Protect SPF 40 100g is a broad-spectrum sunscreen that also hydrates the skin to reduce visible signs of aging. The formula includes Zinc Oxide and Extremozymes to offer reliable UV protection for all skin types. Apply this cream liberally to your face and neck 15 minutes before sun exposure to keep your skin safe and well-nourished.
Earn 1041 SK1N Points
SPF / iS Clinical
Extreme Protect SPF 40 PerfecTint Beige 100g
R2082.00
Offering advanced environmental protection, Extreme Protect SPF 40 PerfecTint Beige 100g shields your skin with Zinc Oxide and Extremozymes. This multi-tasking sunscreen also helps hydrate the skin and reduce the look of wrinkles. Simply apply this tinted formula to your face and neck to combine superior UV defense with a subtle, unified glow.
Earn 1041 SK1N Points
SPF / iS Clinical
Extreme Protect SPF 40 PerfecTint Bronze 100g
R2082.00
Extreme Protect SPF 40 PerfecTint Bronze 100g combines hydration with advanced UV defense in a convenient tinted formula. Powered by Zinc Oxide and Extremozymes, it helps to minimize the appearance of fine lines while protecting against environmental damage. Apply this bronze-toned sunscreen to your face and neck for a smooth, healthy-looking finish that guards your skin against daily sun exposure.
Earn 1041 SK1N Points
Eye Care / iS Clinical
Eye Complex 15g
R2205.00
The 15g Eye Complex delivers targeted hydration to minimize dark circles and puffiness around the eyes. Featuring hyaluronic acid and copper tripeptide growth factors, this treatment refreshes and rejuvenates the skin. Gently pat a small amount into the orbital bone area to soften the look of lines.
Earn 1103 SK1N Points
Cream / iS Clinical
Firming Complex 50g
R3381.00
Firming Complex 50g acts as a potent moisturizer to improve skin elasticity and tighten the appearance of sagging areas. Formulated with Copper Tripeptide Growth Factor and Hyaluronic Acid, it works to smooth out fine lines while hydrating the skin. Massage this cream onto your face and neck morning and evening for a firm and refreshed complexion.
Earn 1691 SK1N Points
Serum / iS Clinical
GeneXC Serum 15ml
R2572.00
The 15ml GeneXC Serum pairs vitamin c with proprietary Extremozymes to defend against visible signs of ageing. This anti-ageing formula brightens the complexion while supporting skin elasticity and repair. Apply three to five drops to clean skin daily, followed by your preferred moisturizer, to maintain a youthful and clear appearance.
Earn 1286 SK1N Points
Serum / iS Clinical
GeneXC Serum 30ml
R4164.00
GeneXC Serum 30ml blends Vitamin C with Extremozymes to protect your skin and address visible signs of aging. This formula helps to improve elasticity and brighten your complexion for a youthful, healthy appearance. Simply smooth 3-5 drops over your face and neck, followed by your preferred moisturizer, to incorporate this restorative treatment into your daily skin care routine.
Earn 2082 SK1N Points
Serum / iS Clinical
Hydra-Cool Serum 15ml
R1568.00
Experience immediate relief with the 15ml bottle of Hydra-Cool Serum, which is infused with Centella Asiatica and Hyaluronic Acid. This lightweight treatment works to calm inflammation and soothe irritated or sun-stressed skin with a refreshing sensation. Pat a few drops onto your face and neck whenever your skin feels dry or requires an extra touch of cooling hydration.
Earn 784 SK1N Points
Serum / iS Clinical
Hydra-Cool Serum 30ml
R2425.00
Deeply hydrate your skin with the 30ml bottle of Hydra-Cool Serum, a soothing treatment featuring Vitamin B5 and Hyaluronic Acid. Designed for those with dry or irritated skin, this serum cools inflammation while leaving your face feeling revitalized. Apply a few drops to clean skin as needed to restore moisture balance and calm your complexion throughout the day.
Earn 1213 SK1N Points
Exfoliator / iS Clinical
Lip Polish 15g
R931.00
Gentle and effective, the 15g Lip Polish uses sucrose, vitamin c, and vitamin e to buff away dry, flaky skin. This exfoliating treatment leaves your lips feeling soft, conditioned, and perfectly prepared for hydration. Simply massage a small amount onto damp lips two to three times a week for a smooth finish.
Earn 466 SK1N Points
Cream / iS Clinical
Moisturizing Complex 50g
R2401.00
Moisturizing Complex 50g is a rich, protective cream formulated with Hyaluronic Acid and Vitamin E to support your natural moisture barrier. It deeply hydrates while calming the skin, making it suitable for all skin types. Use it as the final step in your morning and evening routine by applying a thin, smoothing layer to your face and neck.
Earn 1201 SK1N Points
Cream / iS Clinical
NeckPerfect Complex 50g
R2695.00
The 50g NeckPerfect Complex is a dedicated treatment cream for the neck and décolleté area. Enriched with hydrolyzed quinoa and mixed fruit acids, it helps to tighten and firm the skin while reducing the appearance of lines. Massage upwards onto clean skin twice daily for a smoother and more defined look.
Earn 1348 SK1N Points
Serum / iS Clinical
Poly-Vitamin Serum 15ml
R1764.00
Revitalize compromised skin with the 15ml bottle of Poly-Vitamin Serum, a potent blend of essential vitamins and bio-nutrients. This intensive formula helps to improve overall texture and health for aging complexions. Smooth a few drops over your face and neck to provide your skin with the concentrated care it needs for a healthier, more nourished appearance.
Earn 882 SK1N Points
Serum / iS Clinical
Poly-Vitamin Serum 30ml
R2817.00
Restore compromised skin with the 30ml Poly-Vitamin Serum, a potent blend of vitamins b3, b5, a, and e. This intensive treatment is formulated to hydrate and revitalize mature or stressed complexions. Apply three to five drops to your face and neck to support better skin health and a noticeably improved texture.
Earn 1409 SK1N Points
Serum / iS Clinical
Pro-Heal Serum Advance+ 15ml
R2327.00
The 15ml Pro-Heal Serum Advance+ is a restorative antioxidant formula for sensitive or mature skin. Combining L-ascorbic acid with olive leaf extract and vitamins a and e, it helps soothe redness while improving overall clarity. Use this serum daily to protect your complexion and provide essential nourishment to the skin.
Earn 1164 SK1N Points
Serum / iS Clinical
Pro-Heal Serum Advance+ 30ml
R3870.00
Pro-Heal Serum Advance+ 30ml uses high-strength Vitamin C and olive leaf extract to restore and soothe sensitive or mature skin. This powerful antioxidant treatment improves skin clarity and defends against environmental stressors. Apply 3-4 drops to your face and neck using your fingertips to provide targeted care that keeps your complexion calm, protected, and visibly healthier.
Earn 1935 SK1N Points
Cream / iS Clinical
Reparative Moisture Emulsion 50g
R2572.00
Reparative Moisture Emulsion 50g is a luxurious moisturizer that hydrates and protects your skin while helping to smooth the look of fine lines. Featuring Squalane and Sodium Hyaluronate, it serves as an ideal non-greasy base for your routine. Smooth a small amount over your face and neck morning and evening to keep your skin comfortably hydrated and supported all day.
Earn 1286 SK1N Points
Treatment / iS Clinical
Retinol+ Emulsion 0.3
R2572.00
This high-performance Retinol+ Emulsion 0.3 uses botanical retinol and Extremozymes to target fine lines and texture. Packaged in a 50g bottle, this treatment refines your skin tone while offering essential antioxidant support. Smooth a small amount over your face and neck during your evening routine to begin your journey toward firmer, smoother skin.
Earn 1286 SK1N Points
Serum / iS Clinical
Youth Serum 30ml
R3895.00
Utilizing advanced Extremozymes and copper tripeptide-1, the 30ml Youth Serum supports a resilient skin structure. This anti-ageing formula helps firm the face and neck while smoothing the appearance of fine lines. Glide one or two drops over clean skin and allow it to absorb naturally for lasting results.
Earn 1948 SK1N Points
Treatment / iS Clinical
Sheald Recovery Balm 15g
R735.00
Provide immediate comfort to sensitive or recovering skin with the 15g Sheald Recovery Balm. Rich in ceramides and oat kernel extract, this balm reinforces your natural barrier and delivers essential hydration to irritated areas. Apply a generous amount to clean, dry skin whenever you need protection and nourishment, especially following professional dermatological treatments.
Earn 368 SK1N Points
Treatment / iS Clinical
Sheald Recovery Balm 60g
R1935.00
The 60g Sheald Recovery Balm provides essential nourishment for skin that feels sensitive or compromised. Ceramides, oat kernel extract, and sodium hyaluronate work together to reinforce your natural barrier and soothe redness. Apply a generous amount to dry areas to offer immediate protection and comfort as your skin recovers.
Earn 968 SK1N Points
Serum / iS Clinical
Super Serum Advance+ 15ml
R2327.00
Featuring a 15% concentration of L-ascorbic acid, the 15ml Super Serum Advance+ offers advanced anti-ageing and reparative care. Copper tripeptides and centella asiatica join the vitamin c to help firm and protect your face. Smooth three to five drops over clean skin each morning to support a bright and resilient complexion.
Earn 1164 SK1N Points
Serum / iS Clinical
Super Serum Advance+ 30ml
R3870.00
This 30ml Super Serum Advance+ combines 15% L-Ascorbic Acid with copper tripeptides to brighten and firm your skin. Designed for anti-ageing and environmental protection, the formula provides powerful reparative benefits. Apply 3 to 5 drops to clean skin each morning, following with a moisturizer and sunscreen to shield your face from daily stressors.
Earn 1935 SK1N Points
Exfoliator / iS Clinical
Tri-Active Exfoliating Masque 120g
R2327.00
Refine your complexion with the 120g Tri-Active Exfoliating Masque, a dual-action formula featuring papaya enzymes, bromelain, and salicylic acid. This professional treatment polishes skin to improve texture and control oil. Apply a thin layer to damp skin, leave for a few minutes, and rinse to reveal a smoother and more radiant appearance.
Earn 1164 SK1N Points
Cleanser / iS Clinical
Warming Honey Cleanser 120g
R1176.00
The iS Clinical Warming Honey Cleanser is a 120g formula that gently exfoliates and cleanses your skin. As you massage it onto damp skin, it warms up to help dissolve impurities while papaya enzymes work to refine your complexion. It leaves your face feeling soft and clean without compromising your natural moisture balance.
Earn 588 SK1N Points
Cream / iS Clinical
Youth Complex 30g
R3895.00
Target fine lines with the 30g Youth Complex, a cream designed to improve firmness and elasticity. The blend of copper tripeptide-1, hyaluronic acid, and mixed fruit acids works deeply to hydrate and promote a youthful look. Massage a small amount into your neck and face every morning and evening to maintain smoother skin.
Earn 1948 SK1N Points
Eye Care / iS Clinical
Youth Eye Complex 15g
R2817.00
The 15g iS Clinical Youth Eye Complex targets fine lines and puffiness using copper tripeptides and hyaluronic acid. It is specifically formulated to firm the delicate skin around your eyes for a more rested appearance. Gently pat a small amount into the orbital area morning and evening to provide intense hydration and help brighten your gaze.
Earn 1409 SK1N Points
Cream / iS Clinical
Youth Intensive Crème 100g
R9431.00
Experience intense rejuvenation with this 100g Youth Intensive Crème, an ultra-rich moisturizer for mature skin. Ingredients like copper tripeptide-1, hyaluronic acid, and superoxide dismutase combine to firm the complexion and smooth out wrinkles. Use this luxurious treatment as part of your evening routine to wake up with nourished and radiant skin.
Earn 4716 SK1N Points
Cream / iS Clinical
Youth Intensive Crème 50g
R5757.00
Designed for evening nourishment, the 50g Youth Intensive Crème targets wrinkles with copper tripeptide-1 and superoxide dismutase. This ultra-rich cream provides deep hydration to firm the skin and improve overall texture. Apply a small amount before bed to enjoy a more youthful, radiant complexion by morning.
Earn 2879 SK1N Points
Treatment / iS Clinical
Youth Lip Elixir 3.5g
R1470.00
The 3.5g Youth Lip Elixir provides a sophisticated solution for thirsty lips. Formulated with hyaluronic acid, vitamin c, and shea butter, this treatment works to smooth and plump while offering long-lasting environmental protection. Simply apply a small amount alone or under your favourite lipstick for a polished, hydrated finish that feels comfortable throughout the day.
Earn 735 SK1N Points
SPF / iS Clinical
Lip Protect SPF 35 5g
R585.00
The iS Clinical Lip Protect SPF 35 5g provides broad-spectrum mineral protection while deeply nourishing dry lips with coconut oil and vitamin e. This transparent treatment feels smooth on the skin and keeps the delicate lip area hydrated throughout the day. Apply it liberally to maintain shield-like defense against environmental elements.
Earn 293 SK1N Points
Serum / iS Clinical
Active Serum 15ml
R2156.00
Active Serum 15ml is a professional-grade treatment that refines skin quality by smoothing texture and reducing the appearance of fine lines. This multi-purpose formula uses sugar cane and white willow bark extracts to brighten and clarify your complexion. After smoothing a few drops over your face and neck, a tingling sensation is normal, signaling the serum is working effectively.
Earn 1078 SK1N Points
Serum / iS Clinical
Active Serum 30ml
R3478.00
Professional-grade and powerful, the 30ml Active Serum targets acne, texture, and fine lines. With sugar cane, bilberry, and white willow bark extracts, it works to clarify and brighten your complexion rapidly. You may feel a slight tingling upon application, which is normal as this serum begins to smooth your skin.
Earn 1739 SK1N Points
Cream / iS Clinical
Brightening Complex 30g
R3723.00
Brightening Complex 30g works to lighten hyperpigmentation and promote a more uniform skin tone through a concentrated botanical formula. It uses powerful exfoliants to improve your skin texture and increase overall radiance. Gently apply this treatment to clean skin, specifically focusing on areas with uneven pigmentation to support a clearer, more balanced appearance on your face.
Earn 1862 SK1N Points
Serum / iS Clinical
Brightening Serum 15ml
R2033.00
Brightening Serum 15ml targets hyperpigmentation and uneven skin tone through a blend of potent botanical extracts. This specialized treatment promotes a more uniform and radiant complexion with every application. Apply a small amount to the affected areas on your clean skin once or twice daily to help brighten and clarify the overall appearance of your face.
Earn 1017 SK1N Points
Serum / iS Clinical
Brightening Serum 30ml
R3405.00
The 30ml Brightening Serum features Norway spruce and sugar cane extracts to target areas of uneven tone and pigmentation. By combining botanicals with mild exfoliants, it promotes a uniform and radiant complexion. Apply a small amount to the skin daily to help clarify your tone and improve overall texture.
Earn 1703 SK1N Points
Eye Care / iS Clinical
C Eye Serum Advance+ 15ml
R1666.00
Specifically formulated for the eyes, the 15ml C Eye Serum Advance+ combines L-ascorbic acid and copper tripeptides to reduce puffiness and fine lines. This antioxidant-rich treatment brightens the delicate orbital area while offering protection from the environment. Pat a small amount around the eyes using your ring finger morning and evening.
Earn 833 SK1N Points
Cleanser / iS Clinical
Cleansing Complex 180ml
R1176.00
Cleansing Complex 180ml is a gentle yet effective gel designed to remove impurities while maintaining the moisture of sensitive skin. With Salicylic Acid and botanical extracts, it works to clear your pores and soothe redness without harsh stripping. Massage the cleanser onto your face and neck, then rinse thoroughly to leave your skin feeling clean, refreshed, and balanced.
Earn 588 SK1N Points
Cleanser / iS Clinical
Cleansing Complex 60ml
R612.00
The 60ml Cleansing Complex is a lightweight gel that respects sensitive skin while removing impurities. Centella asiatica, salicylic acid, and chamomile extract work together to balance the skin without stripping away essential moisture. Massage this cleanser onto moistened skin to leave your face feeling clean, calm, and hydrated.
Earn 306 SK1N Points
Exfoliator / iS Clinical
Cleansing Complex Polish 120g
R1176.00
Ideal for managing oil and breakouts, the 120g Cleansing Complex Polish provides a physical and chemical approach to exfoliation. Infused with salicylic acid, chamomile, and centella asiatica, it clarifies the skin during your wash. Massage onto damp skin and rinse thoroughly to maintain a balanced and smooth complexion.
Earn 588 SK1N Points
Toner / iS Clinical
Copper Firming Mist 75ml
R980.00
Copper Firming Mist 75ml serves as a refreshing toner that supports your skin's protective barrier with Copper PCA and Resveratrol. This fine mist delivers an instant cooling sensation, making it a perfect pick-me-up throughout your day. Close your eyes and spritz it over your face and neck to firm and hydrate your complexion whenever you need a boost.
Earn 490 SK1N Points
Frequently asked questions
- Where can I buy iS Clinical in South Africa?
- SK1N stocks iS Clinical online and delivers to every province in South Africa, with a flat R150 delivery fee on every order.
- Does SK1N deliver iS Clinical nationwide?
- Yes. Orders are dispatched within one business day and typically arrive within 2 to 5 business days anywhere in South Africa.
- Can I have iS Clinical delivered every month?
- Any iS Clinical product can be ordered as a monthly replenishment over a 6 or 12 month term, at the same price as a once-off purchase.