Discoloration Defense Serum
R2350.00
SkinCeuticals Discoloration Defense is a new-generation, multi-phase dark spot corrector serum that helps address melasma and post-inflammatory hyperpigmentation (PIH). Suitable for hyperpigmentation and uneven skin tone. Key ingredients include 3% Tranexamic Acid , a synthetically derived ingredient that assists in inhibiting the release of inflammatory mediators, specifically prostaglandins and arachidonic acid, which are involved in melanogenesis. Studies have also demonstrated its ability to address hard-to-treat forms of hyperpigmentation, including post-acne marks. 1% Kojic Acid is an antioxidant and skin-brightener that helps to inhibit melanin production and treat age spots, post-inflammatory hyperpigmentation, and melasma. 5% Niacinamide , also known as vitamin B3, offers proven skin-brightening benefits. HEPES is a synthetically derived acid that activates natural enzymes in the skin to help break the bonds that bind dead skin cells to the surface for even exfoliation. Fragrance-free. Hydroquinone-free. Dr. Webster’s Recommendation: SkinCeuticals Discoloration Defense is a layerable, daily-use serum that targets dark marks, helping to brighten the skin without aggravating it. Ideal for use post-hydroquinone treatment, or as a standalone home care routine with the inclusion of a SkinCeuticals antioxidant serum and retinoid. Always use a high-factor, broad-spectrum sunscreen to protect and prevent the skin against UV-induced hyperpigmentation. Updated formula 04/2026
Earn 1175 SK1N Points with this purchase
SkinCeuticals Discoloration Defense is a new-generation, multi-phase dark spot corrector serum that helps address melasma and post-inflammatory hyperpigmentation (PIH). Suitable for hyperpigmentation and uneven skin tone. Key ingredients include 3% Tranexamic Acid , a synthetically derived ingredient that assists in inhibiting the release of inflammatory mediators, specifically prostaglandins and arachidonic acid, which are involved in melanogenesis. Studies have also demonstrated its ability to address hard-to-treat forms of hyperpigmentation, including post-acne marks. 1% Kojic Acid is an antioxidant and skin-brightener that helps to inhibit melanin production and treat age spots, post-inflammatory hyperpigmentation, and melasma. 5% Niacinamide , also known as vitamin B3, offers proven skin-brightening benefits. HEPES is a synthetically derived acid that activates natural enzymes in the skin to help break the bonds that bind dead skin cells to the surface for even exfoliation. Fragrance-free. Hydroquinone-free. Dr. Webster’s Recommendation: SkinCeuticals Discoloration Defense is a layerable, daily-use serum that targets dark marks, helping to brighten the skin without aggravating it. Ideal for use post-hydroquinone treatment, or as a standalone home care routine with the inclusion of a SkinCeuticals antioxidant serum and retinoid. Always use a high-factor, broad-spectrum sunscreen to protect and prevent the skin against UV-induced hyperpigmentation. Updated formula 04/2026
- Strength
- Niacinamide Kojic Acid Tranexamic Acid HEPES
- Size
- 30ml
- Application
- Serum
- Concern
- Pigmentation
Apply 3-5 drops of Discoloration Defense twice a day after cleansing in the morning and evening. If using in the morning, apply after your SkinCeuticals antioxidant and follow with a SkinCeuticals broad-spectrum sunscreen. Limit sun exposure while using this product & always use a good quality, high factor, broad spectrum sunscreen every day - compliance is vital when treating pigmentation. Do not use on irritated or broken skin. If irritation occurs, discontinue use.
Full Ingredients (INCI)
AQUA / WATER, BUTYLENE GLYCOL, NIACINAMIDE, HYDROXYETHYLPIPERAZINE ETHANE SULFONIC ACID, GLYCERIN, TRANEXAMIC ACID, PROPYLENE GLYCOL, HYDROXYETHYL UREA, KOJIC ACID, CAPRYLYL GLYCOL, ALLANTOIN, CHLORPHENESIN, XANTHAN GUM, DISODIUM EDTA
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What is Discoloration Defense Serum used for?
Discoloration Defense Serum is a serum from SkinCeuticals, formulated for pigmentation. A powerful dark mark correction treatment serum. This is the updated formula.
How do I use Discoloration Defense Serum?
Apply 3-5 drops of Discoloration Defense twice a day after cleansing in the morning and evening. If using in the morning, apply after your SkinCeuticals antioxidant and follow with a SkinCeuticals broad-spectrum sunscreen. Limit sun exposure while using this product & always use a good quality, high factor, broad spectrum sunscreen every day - compliance is vital when treating pigmentation. Do not use on irritated or broken skin. If irritation occurs, discontinue use.
What are the key ingredients in Discoloration Defense Serum?
Discoloration Defense Serum is built around Niacinamide Kojic Acid Tranexamic Acid HEPES. The full INCI list is published on this page, so you can check every ingredient before you commit.
How long does Discoloration Defense Serum take to work?
Brightening is gradual. Expect a visibly more even tone after 8–12 weeks, and keep using daily SPF or the pigment will return. Results depend on consistency, and on daily broad-spectrum SPF, which protects the progress you have made.
Can I use Discoloration Defense Serum with retinol and vitamin C?
Yes, with care. Apply water-based formulas before oil-based ones, and keep strong acids and retinol in separate sessions: vitamin C suits the morning, retinol the evening.
Is Discoloration Defense Serum safe to use during pregnancy or breastfeeding?
Some actives in Discoloration Defense Serum, including retinoids and high-strength acids, are generally avoided during pregnancy and breastfeeding. Please speak to your treating doctor or our skincare advisor before use, and favour gentle, pregnancy-safe alternatives.
How long does one 30ml serum last?
Discoloration Defense Serum is supplied as 30ml. Used at the recommended amount twice daily, most people find a bottle of this size lasts roughly two to three months, though that depends on how far you take it, and whether you cover the neck and décolleté as well as the face.
Is Discoloration Defense Serum genuine, and where can I buy it in South Africa?
Every Discoloration Defense Serum sold on SK1N is sourced through authorised SkinCeuticals distribution and dispatched from South Africa, not grey-market stock. Standard delivery is a flat R150 nationwide, and our consultants can confirm it suits your routine before you buy.
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